Mantell Associates is partnered with a fast-growing Biotech organisation who are seeking a Head of Translational Medicine to join their skilled team.

Head of Translational Medicine - Responsibilities:

• Establish and execute translational research strategies that support our R&D & clinical programs

• Work closely with our CEO and CMO to oversee translational sciences, early clinical development, and early regulatory affairs across a range of potential oncology indications

• Ensure that our clinical-stage antibody programs are on track to reach related objectives and milestones within timelines, in partnership with the clinical operations team, CMO & CEO

• Build the translational medicine function and provide translational leadership to scientific teams supporting clinical programs and make clear recommendations on project or study research strategies, decisions and key next steps

• Apply your broad immunology and oncology drug development expertise to interpret and present study results internally, to executive decision-making bodies and to external stakeholders

• Identify key areas of opportunity for applying translational and clinical sciences strategies, best practices, and experimental methods to clinical-stage product candidates and related development programs

• Communicate scientific progress to management and stakeholders, present work at both internal and external meetings as well as to our Board of Directors

• Lead the integration of translational strategy with preclinical research, leveraging your pharmacology and toxicology knowledge to oversee the execution of phase-appropriate in vitro and in vivo studies

• Identify KOLs, clinical experts and other consultants (individually and via SABs) to define precision medicine approach, translation plan, and preclinical package to support Compass programs at IND and clinical development

Head of Translational Medicine - Requirements:

• PhD or equivalent advanced degree in pharmacology or toxicology in the field of oncology, immunology, or a related area

• 20+ years of industry experience in a pharmaceutical or biotechnology organization in the preclinical and translational space

• Proven experience leading oncology, immunology or immuno-oncology drug development

• Demonstrated ability in implementing translational strategies in clinical drug development, extensive pharmacology and pharmacokinetics experience with monoclonal and bispecific antibodies, strong record of translational and/or scientific research productivity preferred

• Experience with regulatory submissions, creating regulatory documents (INDs, CTAs, NDAs etc.) and interacting with global regulatory agencies

• Ability to develop new leaders, engage scientists, and effectively delegate key priorities

• Comfortable with balancing project objectives and ability to prioritize multiple tasks while keeping to timelines, in a fast-faced environment

• Outstanding verbal and written communication skills, and excellent organizational skills

• Strong interpersonal, influencing, problem solving, and collaboration skills that cross scientific disciplines involved in R&D, clinical operations, and drug development

Mantell Associates is a specialist Pharmaceutical and Life Sciences headhunting firm. For more information on this role, please contact us at +44 (0)20 3854 7700.