Associate Director, Clinical Science

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Posted September 11, 2025
Location Massachusetts, USA
Job TypeFull Time, Permanent
Market Pharma
VerticalScientific

Toby Aldren

Mantell Associates

Mantell Associates is partnered with an innovative precision genetic medicine company, who is seeking a forward-thinking and clinically engaged Associate Director, Clinical Science to join its growing team.

 

This pivotal role sits at the interface of clinical research, translational science, and strategy – driving the advancement of cutting-edge genetic therapies toward impactful patient outcomes.

 

Associate Director, Clinical Science – Responsibilities:

  • Lead scientific strategy and execution for early-to-late clinical and translational programs in precision genetic therapies
  • Develop and oversee clinical development plans, including protocol design, endpoint selection, biomarker strategy, and patient stratification
  • Drive integrated translational science initiatives, collaborating with R&D, biomarker teams, regulatory, and clinical operations to ensure alignment of scientific and clinical objectives
  • Act as the clinical expert internally and externally – engaging with KOLs, investigators, and scientific collaborators – and representing clinical science in cross-functional leadership teams
  • Translate emerging scientific findings and patient insights into strategic recommendations for trial design optimization and clinical innovation
  • Provide clinical oversight across trials, supporting safety, data interpretation, and scientific reporting

 

Associate Director, Clinical Science – Requirements:

  • Advanced degree (MD, PhD, PharmD, or equivalent) with significant experience in clinical development or translational research, particularly in genetic therapies, rare diseases, or precision medicine
  • 5 years in clinical strategy, biomarker development, or clinical science roles within biotech or pharma environments
  • Strong grounding in clinical trial design, biomarker integration, and patient-focused endpoint strategy, ideally with gene therapy or nucleic acid modalities
  • Excellent scientific communication skills, with experience influencing internal and external stakeholders – including investigators, regulators, and KOLs
  • Proven track record of adaptability in high-growth, science-driven biotech environments

 

Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at 44 (0)20 3854 7700.

Tagged as: Scientific

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